Mr Anderson is bang on the mark. Dealing with toxins is definately extra work for your body. Mainly your liver I think. When your liver becomes overworked you mat not digest your food so good. This means you will lose muscle.
I see thousands of people making a big fuss over every single gram of protein in egg or worrying about how much fructose in an apple but then throwing supplements loaded with crap E numbers etc down their necks.